Monday, March 3, 2014

Raspberry Ketones Quickie (What's up with this?!)

Most of us have heard of Raspberry Ketones (RK) by now.  You've probably seen a commercial for them or looked at them in the diet section of your local convenience or grocery store.  I know I wondered if they lived up to the hype, I'm sad to say that the research I've done soo far has left much to be desired.  This doesn't mean that I'm discouraged at the possibility that RK could aid people in their weight loss journey, the truth is RK hasn't been tested on humans in any scientific study, the closest we've gotten to human testing is human flesh testing in test tubes (Hand, 2013).  

What are Raspberry Ketones?
RK is one of the "...200 molecules that contribute to [a raspberry's] distinct flavor" and smell" (Cox, 2013).  RK, specifically, deals with that raspberry smell we love soo well, which is why it is used in products ranging from candles to soaps.  I was surprised to find out that RK "...is actually found in cranberries, blackberries as well as red raspberries..." (Cox, 2013) of various genes.

The initial thoughts that RK could prevent weight gain and promote weight loss is due to its molecular structure, which bears resemblance to the structure of capsaicin. 

So does it work?
Unfortunately, there isn't enough evidence to say if it does or doesn't.  According to Caroline Cederquist, R.D. (2012), none of her patients that added RK to their weight loss regimens noticed a significant change.  We will just have to wait for more scientific trials to be sure.

Also, it is important to keep in mind that those who are experimenting with RK are a biased variable because they don't have a control group to compare their results against and they have personal feelings towards the supplement that could affect their results.

What does the FDA say?
Well, for those that might not know, the FDA does not regulate anything this is considered a supplement.  They don't even regulate energy drinks, by the way.  This is why every bottle you buy of a supplement has the disclaimer.  However, RK was deemed "Generally Recognized as Safe" in the 1960s...at a daily dose of less than 2 milligrams.  The supplements being produced today contain much more than that, the bottle I picked up at the grocery store contains 600mg a serving, that's 1200mg a day!

Are you side effects?
According to WebMD, no.  According to the sources I've listed below, some.  It appears that RK has similar side effects that stimulants have: increased heart rate, heart palpitations, and the shakes.  It may interfere with blood thinners like Coumadin; lower blood sugar levels; and lower risk of bleeding.  However, there isn't enough information to be certain.

So why the hype?
Dr. Oz featured RK on his show back in 2012 and it took off from there.  My local herbalist has to keep an eye on the show because whenever he recommends a supplement people flock to her store to buy it. 

It's similarity to capsaicin and synephrine, which "...is often marketed as a powerful weight loss support supplement" (Clark, 2012).  Synephrine is a stimulant and, according to Shannon Clark (2012), helps boost your metabolism.  The idea of being able to boost your metabolism will be covered at a later date because it is a rather controversial topic.  :)

Final thoughts?
I'll pass on RK and just stick to eating with a focus on eating whole foods and getting at least 30 minutes of rigorous activity a day.

You can purchase the study Anti-obese action of raspberry ketone at: 
http://www.sciencedirect.com/science/article/pii/S0024320505001281

References
Cederquist, C. (December 3, 2012). What's the rave with raspberry ketone?Retrieved from "http://www.huffingtonpost.com/caroline-j-cederquist-md/raspberry-ketone_b_2213936.html".
Cox, L. (September 26, 2013). What is raspberry ketone?. Retrieved from "http://www.livescience.com/39972-raspberry-ketone-supplement-facts.html".
Hand, B. (February 28, 2013). What they don't want you to know about raspberry ketones. Retrieved from "http://www.huffingtonpost.com/becky-hand/raspberry-ketones_b_2727943.html".

Future blog post: What is garcinia cambogia?
http://www.livescience.com/39243-garcinia-cambogia-supplement-facts.html

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